Single-use Bioreactor

Single-use bioreactor is a complete cell culture system with a single-use bioreactor bag which is also known as disposable bag. This disposable bioreactor is perfectly suited for cultivation of various cell lines in suspension.

Single-use bioreactor eliminates the need for CIP/SIP operation and validation. Compared with conventional bioreactor systems linked by fixed stainless steel piping network, the design of overall assembly makes this single-use bioreactor system more conductive to quick installation and start-up, showing great advantages in switching between batches of cultivation and flexibility of cultivation process.

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Structure
BGL-TB Series Single-use Bioreactor with Top-mounted Magnetic Agitator BGL-TB1000L

Based on the stainless steel stirred tank bioreactors which are widely used for years, BGL-TB series single-use bioreactor with top-mounted magnetic agitator is designed and manufactured with advantages of easy assembling of disposable bag, simple operation, time saving and low labor intensity. It is a perfect solution to replace stainless steel bioreactors.

Basic Specifications BGL-TB50L Rated working volume (L): 50 Min. working volume (L): 15 Total volume (L): 65 Bag diameter (cm): Φ35 Width*Length*Height (cm): 47*56*122 Impeller (stage): 1 Impeller diameter (cm): 13 Stirring speed (rpm): 30-300 BGL-TB100L Rated working volume (L): 100 Min. working volume (L): 30 Total volume (L): 130 Bag diameter (cm) : Φ44 Width*Length*Height (cm): 60*70*140 Impeller (stage): 2 Impeller diameter (cm): 16 Stirring speed (rpm): 30-300 BGL-TB250L Rated working volume (L): 250 Min. working volume (L): 75 Total volume (L): 310 Bag diameter (cm): Φ60 Width*Length*Height (cm) : 80*75*160 Impeller (stage) : 2 Impeller diameter (cm): 23 Stirring speed (rpm): 30-200 BGL-TB500L Rated working volume (L): 500 Min. working volume (L): 150 Total volume (L): 650 Bag diameter (cm) : Φ76 Width*Length*Height (cm): 80*110*195 Impeller (stage): 2 Impeller diameter (cm): 29 Stirring speed (rpm): 30-200 BGL-TB1000L Rated working volume (L): 1000 Min. working volume (L): 300 Total volume (L): 1320 Bag diameter (cm) : Φ96 Width*Length*Height (cm): 110*130*240 Impeller (stage): 3 Impeller diameter (cm): 36 Stirring speed (rpm): 20-150 BGL-TB2000L Rated working volume (L): 2000 Min. working volume (L): 600 Total volume (L): 2100 Bag diameter (cm): Φ120 Width*Length*Height (cm): 132*137*321 Impeller (stage): 3 Impeller diameter (cm): 45 Stirring speed (rpm): 20-100 Control Accuracy

Mixing rate	Control accuracy: ±1% rpm
Culture temperature	Control range: 0-40 °C; Control accuracy: ±0.2°C; Resolution: 0.1 °C
Electronic weighing scale	Measuring accuracy: ±0.3%
PH accuracy	Control range: 2-12; Control accuracy: ±0.1; Resolution: 0.01
DO accuracy	Control range: 0-100%; Display range: 0-300%; Control accuracy: ±2%; Resolution: 0.1%
Gas flow	Control accuracy: ±1%; Resolution: 0.1%
Quantity of mass flow meters	5

Standard Configuration of Instruments PLC control unit: Siemens 1200 Quantity of weighing modules: 3 Quantity of pH electrodes: 1 Quantity of DO electrodes: 1 Quantity of tank temperature electrodes: 1 Quantity of pressure sensor: 1 BGL-BB Series Single-use Bioreactor with Bottom-mounted Magnetic Agitator Basic Specifications BGL-BB50L Rated working volume (L):50L Min. working volume (L):10L Total volume (L):65L Bag diameter (cm):Φ35 Width*Length*Height (cm):47*56*122 Impeller (stage):1 Impeller diameter (cm):13 Stirring speed (rpm):30-300 BGL-BB100L Rated working volume (L):100L Min. working volume (L):20L Total volume (L):130L Bag diameter (cm):Φ44 Width*Length*Height (cm):60*70*140 Impeller (stage):2 Impeller diameter (cm):16 Stirring speed (rpm):30-300 BGL-BB250L Rated working volume (L):250L Min. working volume (L):50L Total volume (L):310L Bag diameter (cm):Φ60 Width*Length*Height (cm):80*75*160 Impeller (stage):2 Impeller diameter (cm):23 Stirring speed (rpm):30-300 BGL-BB500L Rated working volume (L):500L Min. working volume (L):100L Total volume (L):650L Bag diameter (cm):Φ76 Width*Length*Height (cm):80*110*195 Impeller (stage):2 Impeller diameter (cm):29 Stirring speed (rpm):30-300 BGL-BB1000L Rated working volume (L):1000L Min. working volume (L):200L Total volume (L):1320L Bag diameter (cm):Φ96 Width*Length*Height (cm):110*130*240 Impeller (stage):3 Impeller diameter (cm):36 Stirring speed (rpm):30-300 BGL-BB2000L Rated working volume (L):2000L Min. working volume (L):400L Total volume (L):2100L Bag diameter (cm):Φ120 Width*Length*Height (cm):132*137*321 Impeller (stage):3 Impeller diameter (cm):45 Stirring speed (rpm):20-300 Control Accuracy

Mixing rate	Control accuracy: ±1% rpm
Culture temperature	Control range: 0-40 °C; Control accuracy: ±0.2°C; Resolution: 0.1 °C
Electronic weighing scale	Measuring accuracy: ±0.3%
PH accuracy	Control range: 2-12; Control accuracy: ±0.1; Resolution: 0.01
DO accuracy	Control range: 0-100%; Display range: 0-300%; Control accuracy: ±2%; Resolution: 0.1%
Gas flow	Control accuracy: ±1%; Resolution: 0.1%
Quantity of mass flow meters	5

Standard Configuration of Instruments PLC control unit: Siemens 1200 Quantity of weighing modules: 3 Quantity of pH electrodes: 1 Quantity of DO electrodes: 1 Quantity of tank temperature electrodes: 1 Quantity of pressure sensor: 1 BGL Series Mobile Control System
BGL Series Control System Human-Machine Interface Main control interface Cultivation control interface PH control interface DO control interface Speed control interface Tank temperature control interface Alarm setting interface Parametric curves interface Data logging interface