Vitamin D3, Cholecalciferol

Vitamin D3, Cholecalciferol

Ingredient: cholecalciferol

IUPAC name: (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol

Othernames: activated 7-dehydrocholesterol, vitamin D3

Molecularformula: C27H44O

Molarmass: 384.64 g/mol

Appearance:white or light yellow, needle-like crystals

Meltingpoint: 83–86 °C

Carrier:corn syrup, sunflower seed oil, sodium caseinate

Particlesize: 80mesh

Losson drying: 5%max

VitaminD is a fat-soluble vitamin that is naturally present in very few foods, addedto others, and available as a dietary supplement. Vitamin D obtained from sunexposure, food, and supplements is biologically inert and must undergo two hydroxylations in the body foractivation. The first occurs in the liver and converts vitamin D to25-hydroxyvitamin D [25(OH)D],also known as calcidiol.The second occurs primarily in the kidney and forms the physiologically active1,25-dihydroxyvitamin D[1,25(OH)2D], also known as calcitriol.

Vitamin D is known as the sunshinevitamin since it is manufactured by the body after being exposed to sunshine.It promotes calcium absorption in the gut and maintains adequate serum calciumand phosphate concentrations to enable normal mineralization of bone and toprevent hypocalcemic tetany. It is also needed for bone growth and bone remodeling by osteoblasts and osteoclasts. Without sufficient vitamin D, bones canbecome thin, brittle, or misshapen. Vitamin D sufficiency prevents rickets inchildren and osteomalacia in adults. Together with calcium, vitamin D also helps protect older adultsfrom osteoporosis. It also helps maintain adequate levels of calcium andphosphorus in the blood. Vitamin D has other roles in the body, includingmodulation of cell growth, neuromuscular and immune function, and reduction ofinflammation. Many genes encoding proteins that regulate cell proliferation,differentiation, and apoptosis are modulated in part by vitamin D. Many cellshave vitamin D receptors.

Weprovide vitamin D3 with a potency of no lower than 500,000 International Unitsper gram. Mainly used as premix compound, our vitamin D3 has stableperformance, thus ensures its uniform distribution. Its liquidity could bearheating at 130℃ for 90minutes.

VitaminD3 should be stored in cool, ventilated place where it can be kept from wateras well as light. It is packed in 25 kg a bag. To ensure best activity, use it in 18 months.