Vitamin B5, Calcium D Pantothenate

Vitamin B5, Calcium D Pantothenate

CASnumber: 137-08-6
Other names: calcium d-pantothenate,medicinal; d-pantothenate calcium; Calcium panthothenate; Pantothenic Acid Calcium Salt; D-( )-pantothenic acid calciumsalt; calcium bis{3-[(2,4-dihydroxy-3,3-dimethylbutanoyl)amino]propanoate}; calcium bis(3-{[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino}propanoate); calcium3-[[(2S)-2,4-dihydroxy-3,3-dimethyl-butanoyl]amino]propanoate
Molecularformula: C18H32CaN2O10
Meltingpoint: 170-172°C
Decompose:195-196 °C
Appearance:white power
Calcium: 8.2―8.6%
Nitrogen: 5.7―6.0%
Specific rotation: ＋25.0°―＋28.5°
Heavy metal: 0.002 max
Arsenic: 0.0003 max
Loss on drying: 5.0 max
Solubility: very soluble in water: insoluble in ethanol, chloroform, diethylether

Found present in virtually all plants and animal foods, vitamin B5 is alsoknown in other forms -Calcium Pantothenate,Pantothenate, and Panthenol. Vitamin B5 is essential to allforms of life. It plays an important role in maintain the health of hair, skinand blood. Actually, it is also essential for the metabolism of food as well asin the formation of hormones and (good) cholesterol. This vitamin occursmainly as coenzyme A(CoA). It is primarily absorbed in the smallintestine via passive diffusion. Transportation in the heart, muscles, andliver cells is done by a sodium active transport. Within the central nervoussystem, adipose, and renal uptake, facilitative diffusion is used.

Pantothenic acid is a component of coenzyme A, an essential coenzymein a variety of reactions that sustain life. CoA is required for chemical reactions that generateenergy from food (fat, carbohydrates, and proteins). The synthesis of essentialfats, cholesterol, and steroid hormones requires CoA, as does the synthesis of the neurotransmitter,acetylcholine, and the hormone, melatonin. Heme, a component of hemoglobin, requires a CoA-containing compound for itssynthesis. Metabolism of a number of drugs and toxins by the liver requires CoA.

The acyl-carrierprotein requires pantothenic acid in the form of 4'- phosphopantetheine for its activity as an enzyme. Both CoA and the acyl-carrierprotein are required for the synthesis of fatty acids. Fatty acids are acomponent of some lipids, which are fat molecules essential for normal physiologicalfunction.

Administration of pantothenic acid orally and application of pantothenol ointment to the skin have been shown to accelerate the closure of skin woundsand increase the strength of scar tissue in animals. Adding calcium-D-pantothenate to cultured humanskin cells given an artificial wound increased the number of migrating skincells and their speed of migration, effects likely to accelerate wound healing.Deficiencycan result in acne and paresthesia (skintingling)

Vitamin B5 should be stored in cool, dry, tidy anddark place. Keep away from hazard and harmful substance. Use it in two years. Weprovide best products with a preferable price. Together with best service, ourcompany is very competitive in the market.