Ribonuclease
Source: Bovine Pancreas
General description
PancreaticRibonuclease (RNase I)catalyzes cleavage of the phosphodiester bond between the 5'-ribose of anucleotide and the phosphate group attached to the 3'-ribose of an adjacent pyrimidinenucleotide forming a 2',3'-cyclic phosphate which may then be hydrolyzed to thecorresponding 3'-nucleoside phosphate. Ribonuclease A has a molecular weight of13,700 daltons. It operates in an optimum pH range of 7.0-7.5.
The high purity Ribonuclease of Beijing GeyuantianrunBio-tech Co., Ltd.. is purified by re-crystallization, and then by Chromatography andultra-filtration.
Specification
Items | Specification | Standard |
Appearance | White lyophilized powder | Enterprise Standard |
Solution Transparent | Not more opalescent than ref.suspensionⅡ | Enterprise Standard |
Loss on drying | No more than 5.0% | USP33 |
DNA | Not detectable | Enterprise Standard |
Activity | No less than 50kunitz units/mg, calculated on the dried basis | Enterprise Standard |
Storage
Pancreatic Ribonuclease should be sealed stored at darkplaces, at temperature of 2-8℃.
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